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Linking genotype to phenotype: improving functional annotation in dairy cattle breeding

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Linking genotype to phenotype: improving functional annotation in dairy cattle breedingFunctional annotation describes known or predicted roles of a DNA variant or DNA sequences molecular function on the expression of a trait phenotype. Since whole genome sequencing became economical, software was developed to filter variants based on these annotations. Functional annotation has helped identify causative variants, which in turn increase prediction accuracy of genomic selection, particularly across breeds and multibreed populations. The

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