ACE-031

ACE-031Overview ACE 031, also known as ramatercept or ACVR2B Fc, is a recombinant fusion protein consisting of the extracellular domain of human activin receptor type IIB (ActRIIB) fused to the Fc portion of human IgG1. It functions as a soluble decoy receptor that binds myostatin (GDF 8) and other TGF superfamily ligands (activins, GDF 11), preventing their interaction with endogenous receptors. It is widely used in laboratory and preclinical research as a

Molecular Weight: 1419

acetylated active fragment (17–23) of Thymosin Beta-4

GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) found in human plasma

and restoration of gut barrier integrity

modified with a tyrosine at the N-terminus and containing a disulfide bridge

Angiogenesis and Wound Healing Models: In rodent excisional wound

and extended mean and maximum lifespan in rodents by up to 12–17%

β-common receptor/CD131 heterodimer) without stimulating erythropoiesis

MOTS-c administration improved glucose tolerance

CAS Number: 77591-33-4 (parent Thymosin β4)

Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂

90 g/mol (acetate salt